First Study to Reveal How Paracetamol Works

ScienceDaily (Nov. 22, 2011) — Researchers at King’s College London have discovered how one of the most common household painkillers works, which could pave the way for less harmful pain relief medications to be developed in the future.

Paracetamol is a widely-used analgesic (painkiller) and the main ingredient in everyday medications such as cold and flu remedies. Although discovered in the 1890s and marketed as a painkiller since the 1950s, exactly how it relieves pain was unknown.

This study, funded by the Medical Research Council (MRC) and recently published in Nature Communications, shows for the first time the principal mechanism of action for one of the most-used drugs in the world.

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