Filters That Reduce ‘brain Clutter’ Identified

Until now, it has been assumed that people with conditions like ADHD, Tourette syndrome, obsessive compulsive disorder and schizophrenia — all of whom characteristically report symptoms of "brain clutter" — may suffer from anomalies in the brain’s prefrontal cortex.

Damage to this brain region is often associated with failure to focus on relevant things, loss of inhibitions, impulsivity and various kinds of inappropriate behaviour. So far, exactly what makes the prefrontal cortex so essential to these aspects of behaviour has remained elusive, hampering attempts to develop tools for diagnosing and treating these patients.

Colored stimuli shown to animals during trials. The area shaded in red represents the dorsolateral prefrontal cortex of the brain. (Credit: Therese Lennert)

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